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Author Topic: Nobel Prize Awards 2018  (Read 50085 times)
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PeDe
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« on: October 01, 2018, 05:46:56 PM »

It's starting peeps, it's starting


This year’s Nobel Prize winners will be revealed throughout the first two weeks of October. You’ll find the details here as they are announced, along with links to Quartz’s coverage of the people and ideas behind the awards.

Monday, Oct. 1
The Nobel Prize in physiology or medicine has been awarded to James Allison and Tasuku Honjo “for their discovery of cancer therapy by inhibition of negative immune regulation.”

Tuesday, Oct. 2
The Nobel Prize in physics will be announced at 11.45 am local time in Sweden (CEST).

Wednesday, Oct. 3
The Nobel Prize in chemistry will be announced at 11.45 am local time in Sweden (CEST).

Friday, Oct. 5
The Nobel Peace Prize will be announced at 11.00 am local time in Norway (CEST).

Monday, Oct. 8
The Sveriges Riksbank Prize in Economic Sciences in Memory of Alfred Nobel will be announced at 11.45am local time in Sweden (CEST)
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PeDe
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« Reply #1 on: October 01, 2018, 05:50:08 PM »

October 1
The Nobel Prize in physiology or medicine has been awarded to James Allison and Tasuku Honjo “for their discovery of cancer therapy by inhibition of negative immune regulation.”

American and Japanese immunologists are awarded Nobel Medicine Prize for research for their work on cancer therapy.

Two immunologists, James Allison from the University of Texas Austin and Tasuku Honjo from Kyoto University, have won the 2018 Nobel Medicine Prize for research that has revolutionised the treatment of cancer.

The pair were honoured 'for their discovery of cancer therapy by inhibition of negative immune regulation,' the Nobel Assembly said.

Immune checkpoint inhibitor therapy targets proteins made by some immune system cells, as well as some cancer cells. The proteins can stop the body's natural defences from killing cancer cells. The therapy is designed to remove this protein 'brake' and allow the immune system to more quickly get to work fighting the cancer.

'Therapies based on his discovery proved to be strikingly effective in the fight against cancer,' the Stockholm-based assembly said in a statement.

Releasing the potential of immune cells to attack cancers joins other treatments including surgery, radiation and drugs. In 2014 Professor Allison and Professor Honjo won the Tang Prize which is touted as Asia's version of the Nobels.

The duo will share the Nobel prize sum of nine million Swedish kronor (about $1.01 million/ 870,000 euros/ £770,000). They will receive their prize from King Carl XVI Gustaf at a formal ceremony in Stockholm on December 10.






Professor James Allison from the University of Texas received his bachelor's degree in 1969 and doctorate in 1973 in biological science at The University of Texas at Austin.

He is now chair of immunology and executive director of the Immunotherapy Platform at the University of Texas MD Anderson Cancer Center.

For decades, Professor Allison has studied how certain immune cells in our bodies, called T-cells, work.

T-cells identify and wipe out foreign invaders, including bacteria and viruses.

Professor Allison discovered that one molecule in T-cells, called CTLA-4, acts as a kind of brake.

Some cancers defend themselves from our immune systems by activating these brakes.

Professor Allison is currently involved in clinical trials that combine his anti-cancer drug with a second one that helps T-cells go after cancer.

Metastatic melanoma patients started receiving this combined therapy more than three years ago, and so far, three in five are still alive.





Professor Tasuku Honjo was born in 1942 and did his undergraduate at the School of Medicine at Kyoto University.

He stayed on for his PhD and is now a professor emeritus at the university.

His work has been described as initiating a historic turning point—a 'penicillin moment'—in the fight against cancer.

He discovered an immunoregulatory molecule called PD-1.

This has led to a new class of cancer drugs that unleash the body's own immune system against cancer.

PD-1 is a protein produced on the surface of some T-cells and can be thought of as the 'brakes' of the immune system.

The protein helps keep the immune system from running out of control and attacking normal, healthy cells.

Professor Honjo thought that if PD-1 could be blocked then perhaps a patient's own immune system could be used against cancer cells.

Today, PD-1 inhibitors such as the drugs nivolumab and pembrolizumab are showing promise for more effective treatment of certain types of cancer, such as melanoma.

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cordtx

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« Reply #2 on: October 02, 2018, 12:40:58 AM »

Yay my Texas peeps!!
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Elissa

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« Reply #3 on: October 05, 2018, 07:07:03 PM »

The Nobel Peace Prize has been revealed today (and IMO  it's extremely well-deserved Thumb up )

to both Dr Denis Mukwege of Congo and Nadia Murad of Iraq.

Dr Mukwege has treated thousands of women who were victims of gang wartime rape.

https://en.wikipedia.org/wiki/Denis_Mukwege

Nadia Murad is a Yazidi-Iraqi human rights activist and a former Isis prisoner and slave.

https://en.wikipedia.org/wiki/Nadia_Murad



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Maria
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« Reply #4 on: October 05, 2018, 07:15:58 PM »

The Nobel Peace Prize has been revealed today (and IMO  it's extremely well-deserved Thumb up )

to both Dr Denis Mukwege of Congo and Nadia Murad of Iraq.

Dr Mukwege has treated thousands of women who were victims of gang wartime rape.

https://en.wikipedia.org/wiki/Denis_Mukwege

Nadia Murad is a Yazidi-Iraqi human rights activist and a former Isis prisoner and slave.

https://en.wikipedia.org/wiki/Nadia_Murad





The Nobel peace price is awarded in Oslo though Smiley
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Elissa

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« Reply #5 on: October 05, 2018, 07:47:40 PM »

My bad  Blush

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karma chamelion

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« Reply #6 on: October 05, 2018, 08:10:02 PM »

Truly deserving and amazing people doing wonderful things for their fellow human beings. I love reading the stories of their accomplishments, thanks so much PeDe! Star

If only they didn't have to rub elbows with a human petri dish at the Swedish awards dinner. So disgraceful that she is allowed anywhere near such accomplished people.
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Maria
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« Reply #7 on: October 05, 2018, 08:29:00 PM »

My bad  Blush



It is confusing that the awards are split up in two ceremonies. Smiley
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PeDe
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« Reply #8 on: October 05, 2018, 08:34:16 PM »

Nobel in PHYSICS





Gérard Mourou from France
Mourou at the École Polytechnique near Paris, and Strickland at the University of Waterloo in Ontario, each receive a quarter of the prize for work that paved the way for the shortest, most intense laser beams ever created. Their technique, named chirped pulse amplification, is now used in laser machining and enables doctors to perform millions of corrective laser eye surgeries every year.






Donna Strickland from Canada
Giving her reaction to the call from Stockholm early on Tuesday morning, Strickland said: “First of all, you have to think it is crazy.” She is the first woman to win the physics Nobel since Maria Goeppert Mayer was honoured in 1963 for her work on the nuclear shell structure. Strickland becomes only the third woman in history to win the physics prize, and the only living female physics laureate.







Arthur Ashkin from the United States
Ashkin, an affiliate of Bell Laboratories in New Jersey, wins half of the prize for his development of “optical tweezers”, a tractor beam-like technology that allows scientists to grab atoms, viruses and bacteria in finger-like laser-beams. The effect was demonstrated by the award committee by levitating a ping pong ball with a hairdryer. Ashkin is the oldest ever Nobel prize winner - but the 96-year-old is still busy with fresh research.
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PeDe
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« Reply #9 on: October 05, 2018, 08:41:12 PM »


Nobel in CHEMISTRY




Georg Smith from the Unites States
Smith, professor emeritus of biological sciences at the University of Missouri in Columbia, was named Wednesday as a co-winner of the prestigious award for his efforts in harnessing evolution to produce new enzymes and antibodies. Smith’s political activity has made him a controversial figure at the University of Missouri, where he is a tenured professor, and a target of pro-Israel groups. He appears on the controversial Canary Mission website, which publishes online dossiers on pro-Palestinian professors, students and campus speakers, and has been referenced by Israeli officials when refusing activists entry to the country.






Frances Arnold from the United States
Nobel chemistry winner Frances Arnold is celebrating her prize with her students and fellow faculty members at the California Institute of Technology. The 62-year-old shared the Nobel for her work on the directed evolution of antibodies with Cambridge University scientist Greg Winter and George Smith of the University of Missouri.






Greg Winter from England
Sir Greg Winter, of the University of Cambridge, has been jointly awarded the 2018 Nobel Prize in Chemistry, along with Frances Arnold and George Smith, for his pioneering work in using phage display for the directed evolution of antibodies, with the aim of producing new pharmaceuticals. The first pharmaceutical based on this method, adalimumab, was approved in 2002 and is used for rheumatoid arthritis, psoriasis and inflammatory bowel diseases. Since then, phage display has produced antibodies that can neutralise toxins, counteract autoimmune diseases and cure metastatic cancer.
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Duchess of Verona

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« Reply #10 on: October 05, 2018, 10:20:32 PM »

The Nobel Peace Prize has been revealed today (and IMO  it's extremely well-deserved Thumb up )

to both Dr Denis Mukwege of Congo and Nadia Murad of Iraq.

Dr Mukwege has treated thousands of women who were victims of gang wartime rape.

https://en.wikipedia.org/wiki/Denis_Mukwege

Nadia Murad is a Yazidi-Iraqi human rights activist and a former Isis prisoner and slave.

https://en.wikipedia.org/wiki/Nadia_Murad

I sincerely hope that neither of these well deserving Nobel winners have to sit next to Slitzerella. That's just a bridge to far considering her past and what they won the award for.




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Paulina

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« Reply #11 on: October 06, 2018, 06:05:48 AM »

The Nobel Peace Prize has been revealed today (and IMO  it's extremely well-deserved Thumb up )

to both Dr Denis Mukwege of Congo and Nadia Murad of Iraq.

Dr Mukwege has treated thousands of women who were victims of gang wartime rape.

https://en.wikipedia.org/wiki/Denis_Mukwege

Nadia Murad is a Yazidi-Iraqi human rights activist and a former Isis prisoner and slave.

https://en.wikipedia.org/wiki/Nadia_Murad

I sincerely hope that neither of these well deserving Nobel winners have to sit next to Slitzerella. That's just a bridge to far considering her past and what they won the award for.





Fortunately the peace prize is in Oslo. Anyone they sit next to will be quite fine. MM, though a boring dresser, seems way better than Snakey. She still had my all time favorite wedding dress. If I won that prize, I’d want to sit by the king and queen ad ML.
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Lady Adelaide

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« Reply #12 on: November 02, 2018, 08:19:40 AM »

Madeleine and Chris are not attending this year

https://www.svenskdam.se/...mmer-inte-hem-till-nobel/
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lynda

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« Reply #13 on: November 02, 2018, 02:34:06 PM »

The Nobel Peace Prize has been revealed today (and IMO  it's extremely well-deserved Thumb up )

to both Dr Denis Mukwege of Congo and Nadia Murad of Iraq.

Dr Mukwege has treated thousands of women who were victims of gang wartime rape.

https://en.wikipedia.org/wiki/Denis_Mukwege

Nadia Murad is a Yazidi-Iraqi human rights activist and a former Isis prisoner and slave.

https://en.wikipedia.org/wiki/Nadia_Murad





well deserved.     Trump wanted this award in the worst way and was willing to do anything for it.....................               
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Principessa

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« Reply #14 on: November 02, 2018, 02:43:24 PM »

Only because predecessors of Trump managed to get awarded?

BTW He could perhaps participate in the Ig Nobel awards Wink Smiley

https://www.improbable.com/ig/
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